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KMID : 0370019920060000109
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Chung-Ang Journal of Pharmacal Sciences
1992 Volume.6 No. 0 p.109 ~ p.115
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Uridylation of U6 RNA in Nuclear Extracts of Fat Body of Sarcophaga peregrina Larvae and NIH-Sape-4 Cells
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Abstract
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The uridylation of U6 RNA in a nuclear extract of Sacophaga peregrina fat body and NIH-Sape-4 was examined. Nuclear extract of fat body and NIH-Sape-4 contained U6 RNA, but did not have U6 RNA uridylation enzyme activity. In a previous experiment, we found 105bp uridylated U6 RNA in a nuclear ectract of Ehrlich asictes tumor cells, in this experiment we could find new 125 bp uridylated band. Contrary to nuclear extract of mouse Ascites tumor cell, biological meaning of hetero geneous size band(125bp) of Sarcophaga peregrina and NIH-Sape-4 is unknown. More experimental results may suggest important function of new band(125bp).
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KEYWORD
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